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Table 2 Abundance of NG2, PDGFR alpha, CD11b, and PDGFR beta expressing cells in wild type and NG2 null mice 1, 2, and 6 weeks after lysolecithin injection.

From: Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord

  

NG2 (%)

PDGFRα (%)

CD11b (%)

PDGFRβ (%)

Sham

WT

6.12 ± 1.7c

8.32 ± 2.1c

-

6.62 ± 0.9c

 

KO

-

6.77 ± 2.6c

-

4.82 ± 1.4c

1W

WT

100 ± 8.2

100 ± 11.5

100 ± 9.1

100 ± 17.7

 

KO

-

72.69 ± 16.8*

33.23 ± 10.3***

60.59 ± 15*

2W

WT

75.45 ± 6b

111.4 ± 1.9

174.83 ± 18.6c

121.71 ± 18.7

 

KO

-

89.7 ± 6.6***

103.13 ± 16.6c**

87.71 ± 12.4a*

6W

WT

23.99 ± 11.7c

33.01 ± 4.9c

6.41 ± 0.8c

33.83 ± 2.6c

 

KO

-

40.8 ± 6.4a

4.21 ± 1.3c*

44.69 ± 7*

  1. The abundance of various cell types (NG2+, PDGFRα+, CD11b+, PDGFRβ+) in demyelinated lesions from 1-6 weeks post-lysolecithin injection is illustrated by normalizing cell density values to cell densities found in wild type mice at 1 week post-surgery (these 1 week values are designated as 100%). Values represent means ± S.D. Statistically significant differences are indicated by * < 0.05; ** < 0.01; *** < 0.001 when values were compared between WT and NG2 null mice at the same post-injection week. a < 0.05; b < 0.01; c < 0.001 represent statistically significant differences between values obtained for mice of the same genotype when compared to the 1st week post-injection.