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Table 2 Abundance of NG2, PDGFR alpha, CD11b, and PDGFR beta expressing cells in wild type and NG2 null mice 1, 2, and 6 weeks after lysolecithin injection.

From: Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord

   NG2 (%) PDGFRα (%) CD11b (%) PDGFRβ (%)
Sham WT 6.12 ± 1.7c 8.32 ± 2.1c - 6.62 ± 0.9c
  KO - 6.77 ± 2.6c - 4.82 ± 1.4c
1W WT 100 ± 8.2 100 ± 11.5 100 ± 9.1 100 ± 17.7
  KO - 72.69 ± 16.8* 33.23 ± 10.3*** 60.59 ± 15*
2W WT 75.45 ± 6b 111.4 ± 1.9 174.83 ± 18.6c 121.71 ± 18.7
  KO - 89.7 ± 6.6*** 103.13 ± 16.6c** 87.71 ± 12.4a*
6W WT 23.99 ± 11.7c 33.01 ± 4.9c 6.41 ± 0.8c 33.83 ± 2.6c
  KO - 40.8 ± 6.4a 4.21 ± 1.3c* 44.69 ± 7*
  1. The abundance of various cell types (NG2+, PDGFRα+, CD11b+, PDGFRβ+) in demyelinated lesions from 1-6 weeks post-lysolecithin injection is illustrated by normalizing cell density values to cell densities found in wild type mice at 1 week post-surgery (these 1 week values are designated as 100%). Values represent means ± S.D. Statistically significant differences are indicated by * < 0.05; ** < 0.01; *** < 0.001 when values were compared between WT and NG2 null mice at the same post-injection week. a < 0.05; b < 0.01; c < 0.001 represent statistically significant differences between values obtained for mice of the same genotype when compared to the 1st week post-injection.