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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment

Figure 3

Dose-dependent rise in activity of ROS-scavenging enzymes with PQ treatment in three regions of mouse brain. PQ treatment with different doses of PQ (5, 10, 20, 40, 80 mg/kg b.w.) enhanced the activities of catalase (A), GST (B) and SOD (C) in SN, hippocampus and FC of mouse brain. The activities of the enzymes indicate the status of ROS in tissues as described in the Results and Discussion sections. Enzyme activity is presented as μmole/min/mg protein (for catalase and SOD activity) or as nmole/min/mg protein (for GST activity) as indicated in the figures. Asterisks (*) indicate significant differences (p < 0.05, ANOVA) in values for different doses compared to controls. The same letter indicates nonsignificant differences and different letters indicate significant differences (p < 0.05, Student's t-test) between groups.

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Journal of Neuroinflammation

ISSN: 1742-2094