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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment

Figure 5

Dose-dependent effects of PQ on ROS-scavenging enzymes in blood plasma and peripheral tissues. Lethal doses of PQ (20, 40, 80 mg/kg b.w.) enhanced the activities of catalase (A), GST (B) and SOD (C) in blood plasma and peripheral tissues (lung, liver and kidney) of mice. The activities of these enzymes indicate the status of ROS in tissues and blood plasma. Enzyme activity is presented as μmole/min/mg protein (for catalase and SOD activity) or as nmole/min/mg protein (for GST activity) as indicated in the figures. Asterisks (*) indicate significant differences (p < 0.05, ANOVA) in values for different doses compared to controls. The same letter indicates nonsignificant differences and different letters indicate significant differences (p < 0.05, student t-test) between groups.

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