Figure 3From: The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation Cytokine mRNA expression in the brain 24 hours after SNCA or BSA injection into the substantia nigra. mRNA levels of (A) NFĸB; (B) TNFα; (C) IL-1β; (D) IL-6; (E) TGFβ and (F) COX-2 measured as values relative to GAPDH and normalized to levels within the contralateral hemisphere of control animals. Error bars indicate mean ± SEM. Dotted line represents basal levels in naïve animals. * indicates a significance of P < 0.05 when compared to naïve animals; **indicates P < 0.01 and *** indicates P < 0.005.Back to article page