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Figure 6 | Journal of Neuroinflammation

Figure 6

From: The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation

Figure 6

Cytokine mRNA expression in the brain 24 hours after SNCA, BSA or LPS injection into the substantia nigra with and without peripheral LPS challenge. mRNA levels of (A) NFkB; (B) TNFα; (C) IL-1β; (D) IL-6; (E) TGFβ and (F) COX-2 measured as values relative to GAPDH and normalized to levels within the contralateral hemisphere of control animals. Bars show mean ± SEM. * indicates a significance of P < 0.05 when compared to non-LPS-injected control animals; **indicates P < 0.01 and *** indicates P < 0.005.

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Journal of Neuroinflammation

ISSN: 1742-2094