Figure 8From: The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation Cell death in injected hemisphere 24 h after SNCA, BSA or LPS injection into the substantia nigra with and without peripheral LPS challenge. TUNEL staining was clearly visible in LPS-injected (A) animals but TUNEL was rarely seen in SNCA injected animals (B). No TUNEL staining was observed in BSA-injected brain (C; representative image). Nuclease treated positive control section (D). Data are mean ± SEM, *** indicates a significance of P < 0.005 when compared to the contralateral hemisphere. Scale bar represents 10 μm.Back to article page