Figure 2
Functional polarity to IL-6 in BMEC permeability of HIV-1 (A) and TEER (B). BMECs were exposed to IL-6 (1, 10, and 100 ng/mL) in the luminal or abluminal chamber for 4 hr. In panel A, results are expressed as % of control. The control values of permeability coefficient for 131I-HIV-1 in panel A was 1.03 ± 0.11 × 10-5 and 1.07 ± 0.08 × 10-5 cm/min for the luminal and abluminal control, respectively. Values are means ± SEM (n = 3-12). *P < 0.05, **P < 0.01, ***P < 0.001, significant difference from each corresponding control.