Figure 4From: CXCR7 antagonism prevents axonal injury during experimental autoimmune encephalomyelitis as revealed by in vivoaxial diffusivity Axial diffusivity defined abnormal VLWM volume correlates with clinical severity. Linear regression analysis of mean clinical score during recovery phase as a function of axial diffusivity (A) and injured VLWM (B) (A, R2 = 0.5413, F = 33.04, DFn, DFd = 1.0, 28.0, P < 0.0001; B, R2 = 0.6520, F = 43.10, DFn, DFd = 1.0, 23.0, P < 0.0001). Area-under-curve (AUC) as a function of injured VLWM showed an R2 value of 0.7284 (C, F = 61.69, DFn, DFd = 1.0, 23.0, P < 0.0001).Back to article page