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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice

Figure 1

Quantification of injury size and neuron death after cryolesion injury in wild type (grey bars) and MT-I/II -/- mice (white bars). Injury size (A) was quantified by measurement of the area of the injury in sections taken from the widest point of the injury site. Neuron death identified by fluoro-jade C labelling (B). Fluorojade-C+ cells were counted in the injury site and the surrounding tissue. Counts were standardised per linear mm (width) of the injury site. Lower case letters indicate significance determined by Tukey's B post-hoc test. Time-points sharing letters indicates lack of statistically significant difference. n = 5-7, error bars = SEM. Representative images of fluoro-jade C staining in the injury site of wild type animals at 1 DPI (C), 3 DPI (D) and 7 DPI (E) with scale bars = 200 μm.

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