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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy

Figure 2

A) The mean amplitude of sEPSC and mEPSC was not different in the axotomy groups of neurons with and without TNFα treatment. Tetrodotoxin application (0.5 μM) decreased sEPSC amplitude in both TNFα treated (n = 12, **P < 0.01) and non-treated (n = 18, ***P < 0.001) superficial dorsal horn neurons after axotomy. B) The reduction of sEPSC amplitude after TTX application was similar in both TNFα treated (**P < 0.01) and non-treated (**P < 0.001) neurons.

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