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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide

Figure 6

LPS increases the expression of tryptophan dioxygenases, but GPE does not attenuate this response. Mice were treated as in Figure 5. Steady-state mRNA expression, of three enzymes that metabolize tryptophan to kynurenine, IDO1 (A, B), IDO2 (C) and TDO2 (D), was quantified by real-time rtPCR in the prefrontal cortex and expressed relative to GAPDH. n = 11-12.

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Journal of Neuroinflammation

ISSN: 1742-2094