Figure 7From: Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide LPS depresses the expression of neurotrophic factors, but GPE does not alter the LPS response. Mice were treated as in Figure 5. Steady-state mRNA expression of several neurotrophic factors, IGF-I (A), VEGF (B) and BDNF (C, D), was quantified by real-time rtPCR in the prefrontal cortex and expressed relative to GAPDH. n = 11-12.Back to article page