IRF7-KO mice develop more severe EAE. A) Clinical score of mice with EAE. IRF7 deficient mice (n = 8) developed more severe EAE than WT B6 control (n = 16) as indicated by the asterisk. B) Change in whole body weights as percent of weight one day prior to immunization (Day 0). * P < 0.05, ** p < 0.01.