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Table 1 Relative incidence, onset, and severity of EAE in IRF7-deficient and control mice

From: Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

  Incidence Onset (day) # mice with EAE that did not reach Grade 3 # mice reaching Grade 5a # mice showing remissionb
Wild-type 29/39 12.99 ± 1.0 11/29 4/29 7/29
IRF7-KO 28/30 12.07 ± 0.7 6/28 12/28 2/28
  1. a: Progression to Grade 5 was in all cases rapid and resulted in euthanasia before day 18.
  2. b: Reduction in severity of EAE by one grade was defined as remission.