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Table 1 Relative incidence, onset, and severity of EAE in IRF7-deficient and control mice

From: Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

 

Incidence

Onset (day)

# mice with EAE that did not reach Grade 3

# mice reaching Grade 5a

# mice showing remissionb

Wild-type

29/39

12.99 ± 1.0

11/29

4/29

7/29

IRF7-KO

28/30

12.07 ± 0.7

6/28

12/28

2/28

  1. a: Progression to Grade 5 was in all cases rapid and resulted in euthanasia before day 18.
  2. b: Reduction in severity of EAE by one grade was defined as remission.
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Journal of Neuroinflammation

ISSN: 1742-2094