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Journal of Neuroinflammation
Table 1 Relative incidence, onset, and severity of EAE in IRF7-deficient and control mice
Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice
# mice with EAE that did not reach Grade 3
# mice reaching Grade 5
# mice showing remission
12.99 ± 1.0
12.07 ± 0.7
: Progression to Grade 5 was in all cases rapid and resulted in euthanasia before day 18.
: Reduction in severity of EAE by one grade was defined as remission.
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