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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain

Figure 6

Immunostaining of cPGES and cell type-specific proteins (NeuN for neurons, CD11b for microglia, and GFAP for astrocytes) in the mouse brain after ICH. A: Immunoreactive staining for cPGES was observed in neuron-like cells in the contralateral striatum (CL). B-C: In the perihematomal region of the striatum, cPGES immunoreactivity did not change significantly between 1 day (B) and 3 days (C). D-F: In the perihematomal region of the striatum, double immunostaining showed that cPGES was present in neurons (D), but not in microglia (E) or astrocytes (F), at 1 day. Scale bar in B-F, 30 μm. Inset in D is a double-stained cell at higher magnification (Scale bar, 15 μm). Quantification analysis (G) confirmed that the number of cPGES immunoreactive cells did not change in the perihematomal region of the striatum between 1 day and 3 days after ICH (n = 3/group, all P > 0.05). Values are means ± S.D.

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