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Figure 7 | Journal of Neuroinflammation

Figure 7

From: Selective adenosine A2Areceptor agonists and antagonists protect against spinal cord injury through peripheral and central effects

Figure 7

Effects of systemic SCH58261- and CGS21680-administration on expression of A 2A receptors. Western blot analysis shows that A2A receptors are detected in the SC of sham-operated animals and that they are substantially increased in SCI mice. SCH58261 and CGS21680 treatment significantly reduced SCI-induced A2A receptors expression. GAPDH was used as internal control. A representative blot of lysates obtained from each mice group is shown. The densitometric analysis is expressed as the mean ± SEM for samples from 10 mice from each group and is normalized by control protein (GAPDH) levels, and reported in bar graphs. One-way ANOVA: *P < 0.01 vs sham; # P < 0.05 vs SCI; # # P < 0.01 vs SCI.

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