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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Selective adenosine A2Areceptor agonists and antagonists protect against spinal cord injury through peripheral and central effects

Figure 8

Effect of systemic SCH58261-administration on JNK MAPK activation. Western blot analysis shows a significant increase in phospho-JNK MAPK (Thr183/Tyr185) 24 h after SCI. SCH58261, intraperitoneally administered three times within 24 h, reduced SCI-induced phospho-JNK MAPK levels. A representative blot of lysates obtained from each mice group is shown. The densitometric analysis is expressed as the mean ± SEM for samples from 10 mice from each group and is normalized by control protein (β-actin) levels, and reported in a bar graph. One-way ANOVA: *P < 0.01 vs sham; ##P < 0.05 vs SCI.

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Journal of Neuroinflammation

ISSN: 1742-2094