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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

Figure 1

Proliferation profiles assessed by Ki67 immunostaining in host, peritumor and tumor fractions obtained by neuronavigation. Spectroscopic Cho/NAA ratios were evaluated in all voxels of a predetermined axial slice during the MRI examination. Voxels with low, intermediate and high Cho/NAA ratio were chosen to obtain host, peritumor and tumor fractions as described in Methods. Cell proliferation indices for each fraction were determined using immunostaining with Ki67. The percentage of Ki67-positive cells is indicated in each image. H: host tissue; P: peritumor tissue; T: tumor tissue.

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