Figure 1
Iba1 gene expression is enhanced in hSOD1 G93A rats at 3 and 21 days after PSNL. Iba1 mRNA expression (normalized for GAPDH mRNA expression) is strongly increased in the ipsilateral dorsal quadrant of the lumbar spinal cord of transgenic rats at 3 days (A) and at 21 days (B) after PSNL, as compared to WT ligated animals, validating the inflammatory-prone phenotype of hSOD1G93A rats after peripheral nerve injury. Each group included 5 animals, ## p< 0.01, $$$ p< 0.001, *** p< 0.001, ### p< 0.001 after ANOVA and Tukey post-hoc test.