Figure 4From: MyD88 is pivotal for immune recognition of Citrobacter koseri and astrocyte activation during CNS infection† Microglial/macrophage activation in response to C. koseri infection is impaired in MyD88 KO mice. MyD88 KO and WT mice (6 per group) were sacrificed at 24 h following C. koseri exposure, whereupon brain tissues were fixed by paraformaldehyde perfusion and processed for cryostat sectioning. Ten μm thick brain sections were subjected to immunofluorescence staining using Iba-1 (green) and imaged by confocal microscopy (magnification, 10×). Results are representative of six independent animals per group.Back to article page