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Table 3 Clinical features of patients with confirmed neuroborreliosis, stratified into two groups depending on the IL-17 level in cerebrospinal fluid.

From: Indications of Th1 and Th17 responses in cerebrospinal fluid from patients with Lyme neuroborreliosis: a large retrospective study

  IL-17 in CSF
<0.80 pg/mL
n = 68
IL-17 in CSF
>0.80 pg/mL
n = 65
Pleocytosis
median number of cells/μL, (range)
138
(8-384)
184*
(10-1650)
CSF-albumin
S-albumin median, (range)
14.3
(3.4-59.6)
18.1
(3.8-76.0)
Median age
years, (range)
48
(3-87)
14
(3-77)
Median duration of
symptoms before LP
weeks, (range)
2.0
(0.1-25.0)
3.0
(0-32.0)
Cranial nerve palsy
n, (%)
37
(54.4)
33
(50.8)
Muscle and joint pain
n, (%)
32
(47.1)
27
(41.5)
Radiculitis
n, (%)
30
(44.1)
23
(35.4)
Neck pain
n, (%)
22
(32.4)
25
(38.5)
Headache
n, (%)
26
(28.2)
29
(44.6)
Fatigue
n, (%)
17
(25.0)
31*
(47.7)
Parestesias
n, (%)
12
(17.6)
11
(16.9)
Fever >38°C
n, (%)
10
(14.7)
16
(24.6)
Vertigo
n, (%)
4
(5.9)
6
(9.2)
Concentration difficulties
n, (%)
2
(2.9)
2
(3.1)
  1. CSF: cerebrospinal fluid.
  2. LP: lumbar puncture.
  3. S: serum.
  4. n: number of patients.
  5. °C: degrees Celsius.
  6. * significant differences between the two groups. * p < 0.01, ** p < 0.001, *** p < 0.0001.
  7. Patients could have one or several symptoms.