Skip to main content
Figure 5 | Journal of Neuroinflammation

Figure 5

From: Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways

Figure 5

CoMTb suppression of MMP-2 secretion is mediated by the NFκB pathway. (A), Cells were preincubated with helenalin for 2 h and then stimulated with CoMTb. 72 h cell culture supernatants were analyzed by Luminex, confirmed by gelatin zymography (representative zymogram shown). (B), SC-514 inhibition. Bars represent mean values ± SD of three samples, representative of at least duplicate experiments performed in triplicate. Data were analyzed by one-way analysis of variance, followed by Tukey's multiple comparison. **p < 0.01.

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094