Skip to main content
Figure 8 | Journal of Neuroinflammation

Figure 8

From: Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

Figure 8

Axl-/- mice do not clear myelin debris as efficiently as WT mice. Ten micron frozen WT and Axl-/- spinal cord sections were stained with the lipid dye Oil-Red-O (a,b,c,d,g). Myelin debris appears as dense red clumps. Arrowheads in g show sparse Oil-Red-O+ deposits in the WT lesion. Representative 10× (a,b,c,d left panel) and corresponding 40× (a,b,c,d right panel) images are shown for the ventral (a,c) and lateral (b,d) funiculi of WT (a,b) and Axl-/- mice (c,d, e,f,g,h,i) 40× images of sections showing H+E (e), MBP (f), Iba1 (h) and MAC3 (i) for WT and Axl-/- mice.

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094