Skip to main content
Figure 2 | Journal of Neuroinflammation

Figure 2

From: Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

Figure 2

Impact of dexamethasone-21-phosphate on LPS-induced systemic cytokine synthesis. a) IL-1β and b) IL-6 concentrations, as measured by ELISA, in NBH and ME7 animals (18-19 weeks) at 4 hours post-LPS (500 μg/kg) with or without pre-treatment with dexamethasone-21-phosphate (2 mg/kg). ** p < 0.01, *** p < 0.001 by Bonferroni post-hoc test after a significant main effect of treatment by one-way ANOVA. n = 5 for NBH+LPS+dex and ME7+LPS+dex and n = 4 for all other groups. All data have been presented as mean ± SEM.

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094