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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior

Figure 3

IL-6 trans-signaling in BV.2 microglia and Neuro.2A cells. BV.2 and Neuro2A cells were pre-treated for 1 h with 25 ng/mL sIL-6R and A) IL-6-induced STAT3 phosphorylation and B) LPS-induced IL-6 protein secretion were measured at 20 min and 3 h, respectively. Results are an average of 5 independent experiments. Means with different letters are significantly different from one another (P < 0.05).

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