sgp130 facilitates recovery from LPS-induced sickness behavior. Mice were injected ICV with vehicle or 100 ng sgp130 and i.p. with sterile saline or LPS. Social exploratory baseline behavior was measured before LPS injection and at 2, 4, 6, 8, and 24 h post-injection. Bars represent the mean ± SEM (n = 11-12) Means with * are statistically different (P < 0.05) from saline controls.