Table 1 Plasma cytokines 8 h after sgp130 and LPS
| Â | Vehicle (ICV) | sgp130 (100 ng) (ICV) | p < 0.05 interaction | ||||
|---|---|---|---|---|---|---|---|
|  | Saline (i.p.) | LPS (10 μg) (i.p.) | Saline (i.p.) | LPS (10 μg) (i.p.) | sgp130 | LPS | sgp130 × LPS |
IL-1β | 206.82 ± 86.19 | 1113.12 ± 24.48 | 191.10 ± 85.12 | 1543 ± 695.96 | 0.537 | 0.009* | 0.513 |
IL-6 | 142.87 ± 117.79 | 2873.03 ± 994.50 | 96.50 ± 8.41 | 2682.06 ± 669.86 | 0.820 | 0.001* | 0.955 |
TNF-α | 325.89 ± 54.60 | 987.55 ± 104.77 | 322.95 ± 73.31 | 947.93 ± 119.32 | 0.829 | < 0.0001* | 0.852 |
IL-10 | 56.39 ± 23.01 | 407.34 ± 92.56 | 46.72 ± 11.47 | 447.22 ± 174.13 | 0.764 | 0.002* | 0.719 |