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Table 1 Plasma cytokines 8 h after sgp130 and LPS

From: Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior

  Vehicle (ICV) sgp130 (100 ng) (ICV) p < 0.05 interaction
  Saline (i.p.) LPS (10 μg) (i.p.) Saline (i.p.) LPS (10 μg) (i.p.) sgp130 LPS sgp130 × LPS
IL-1β 206.82 ± 86.19 1113.12 ± 24.48 191.10 ± 85.12 1543 ± 695.96 0.537 0.009* 0.513
IL-6 142.87 ± 117.79 2873.03 ± 994.50 96.50 ± 8.41 2682.06 ± 669.86 0.820 0.001* 0.955
TNF-α 325.89 ± 54.60 987.55 ± 104.77 322.95 ± 73.31 947.93 ± 119.32 0.829 < 0.0001* 0.852
IL-10 56.39 ± 23.01 407.34 ± 92.56 46.72 ± 11.47 447.22 ± 174.13 0.764 0.002* 0.719