Journal of Neuroinflammation

Table 1 Effects of sesamin extract on TBARS (nmol/mg protein) and SOD (units/mg protein) in the mice with 2-h KA-induced SE

From: Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation

Variable	Vehicle	Sesamin extract	Naive	P-value ^a	P-value ^b
	M ± SD	M ± SD	M ± SD		(V, S)	(V, N)	(S, N)
15 mg/kg
TBARS	0.96 ± 0.22	0.85 ± 0.10	0.57 ± 0.04	0.001**	0.225	0.0002**	0.004**
SOD	4.18 ± 1.01	5.27 ± 2.01	8.79 ± 1.22	0.005**	0.686	0.003**	0.006**
30 mg/kg
TBARS	0.86 ± 0.14	0.69 ± 0.14	0.59 ± 0.06	0.003**	0.017*	0.001**	0.126
SOD	5.17 ± 1.90	7.54 ± 2.10	9.48 ± 1.17	0.0004**	0.013*	0.0001**	0.049*

M ± SD: mean ± standard deviation. N: naïve. S: sesamin extract. V: vehicle.
^a One-way ANOVA test.
^b Least significant differences post-hoc test. *P < 0.05, **P < 0.01.

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ISSN: 1742-2094

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