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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain

Figure 5

Effect of intrathecal ketamine on SNL-induced pJNK expression. Only a little pJNK expression could be detected in the Sham-Saline group (A), and intrathecal ketamine (300 μg kg-1) had no effect on pJNK expression in sham-operated rats (B). SNL induced significant pJNK expression (C), which could be suppressed by intrathecal ketamine in a dose-dependent manner (D-F). G, statistical analysis of the pJNK expressions after different treatments. *, # or $ each indicates statistically significant difference with P < 0.05 between groups. Four rats in each group. Scale bar: 100 μm. KTM: ketamine.

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