Figure 4
Hypothermia reduces GFAP staining 24 hours after an Et-1-induced insult. Activation of astrocytes as determined by the expression of GFAP in a sham (A), normothermic (B) and hypothermic (C) rat, 24 hours after the administration of Et-1 or Ringer's solution. The graphs below show the overall expression in striatum (D) and cortex (E) separately in sham (n = 4 at 8, 24 and 72 hours and n = 5 at 168 hours), normothermic (n = 4, 6, 5 and 6 at 8, 24, 72 and 168 hours respectively) and hypothermic (n = 5, 6, 7 and 8 at 8, 24, 72 and 168 hours respectively) rats. *Significantly different (p < 0.05) compared to 8 hours as determined by one-way ANOVA with Dunnett post-hoc test. Ā§Significantly different (p < 0.05) from normothermic rats as determined by one-way ANOVA with Dunnett post-hoc test.