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Figure 6 | Journal of Neuroinflammation

Figure 6

From: P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus

Figure 6

Effect of BzATP, OxATP, sTNFp55R, and BzATP+sTNFp55R infusions on SE-induced NF-κB phosphorylation. (A) p65-Ser276 and p65-Ser311 phosphorylation in the CA3 region following SE. Bar = 100 μm. (B) Quantitative analysis of p65-Ser276 phosphorylation in CA3 region following SE (mean ± S.E.M). *Value is significantly different from saline-infused animals, p < 0.05. (C) Quantitative analysis of p65-Ser311 phosphorylation in CA3 region following SE (mean ± S.E.M). *Value is significantly different from saline-infused animals, p < 0.05. (D-E) p65-Ser276 and p65-Ser311 phosphorylations in CA1 and in dentate granule cells following SE. As compared to non-SE animals, there is no difference in p65-Ser276 or p65-Ser311 phosphorylations in these regions 2 days after SE. Bar = 100 μm.

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