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Table 2 Clinical characteristics of human optic nerve samples.

From: Increased expression of cystine/glutamate antiporter in multiple sclerosis

Reference

Code

Gender

Age

PMD (hours)

Duration of MS (years)

MS type

Optic Nerve Alterations

MS Samples

       

MS1

98-176

M

83

7:05

52

PP

No

MS2

99-054

F

58

8:10

20

SP

Yes

MS3

98-185

F

70

8:55

19

PP

Yes

MS4

98-158

F

76

16:31

53

SP

Yes

MS5

98-087

F

55

7:35

> 11

SP

No

MS6

98-179

F

60

8:50

36

PP

Yes

MS7

99-062

F

79

10:00

44

PP

No

MS8

99-025

F

64

7:45

35

SP

Yes

MS9

98-066

F

75

4:50

> 27

PP/SP

No

MS10

01-018

F

48

8:10

8

SP

No

MS11

01-003

M

69

10:00

34

PP

Yes

MS12

99-119

F

38

5:15

10

RR

No

MS13

00-024

F

52

8:25

16

PP/SP

Yes

MS14*

99-109

M

70

6:25

22

SP

Yes

MS15*

99-121

M

51

7:50

29

SP

Yes

MS16*

99-066

M

69

16:45

46

PP

No

Control Samples

       

C1, 14,16

98-101

M

72

6:45

   

C2,5

98-125

F

58

6.15

   

C3

98-104

F

74

7:25

   

C4

98-051

F

94

16:50

   

C6

98-061

F

64

6:00

   

C7

98-042

F

79

9:45

   

C8

98-148

F

54

5:35

   

C9

98-112

F

84

9:20

   

C10, 13

00-050

F

52

6:50

   

C11

00-090

M

70

7:45

   

C12

00-025

F

41

13:30

   

C15

98-127

M

56

5:25

   
  1. Optic nerve alterations consisted of macroscopic plaques, atrophy and/or optic neuritis.
  2. Abbreviations: Reference, Netherlands Brain Bank bar-coded numbers; A, microarrays; qPCR, real-time quantitative PCR; IH, immunohistochemistry; C, control; MS, multiple sclerosis; M, male; F, female; PMD, postmortem delay; PP, primary progressive; SP, secondary progressive; RR, relapsing remitting. * These samples have been used only for immunohistrochemistry