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Table 2 Changes in brain gene expression of C57BL/6 female mice fed HFD ± BM

From: Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation

Gene Name Symbol Con HFD HFD + BM
Sirtuin 1 Sirt1 1.0 0.86 0.88
Sirtuin 3 Sirt3 1.0 0.72 1.28
Sirtuin 7 Sirt7 1.0 0.99 1.14
Forkhead box O3a Foxo3a 1.0 2.92 1.32
Forkhead box O1 Foxo1 1.0 0.65 0.5
Superoxide dismutase 2, mitochondrial Sod2 1.0 1.32 1.48
Glutathione S-transferase, pi 1 Gstp1 1.0 0.76 1.03
Glutathione peroxidase 4 Gpx4 1.0 0.9 1.10
*Interleukin 10 Il10 1.0 1.76 Absent
*Interleukin 16 Il16 1.0 16.06 Absent
*Interleukin 22 Il22 1.0 10.80 Absent
*Interleukin 17 receptor B Il17rb 1.0 0.597 Absent
*Nuclear factor of kappa B1 NfκB1 1.0 8.22 Absent
Eukaryotic translation initiation factor 2, subunit 2 (beta) Eif2s2 1.0 0.77 1.03
Eukaryotic translation initiation factor 2B, subunit 2 beta Eif2b2 1.0 0.90 1.04
Eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked Eifs3x 1.0 0.79 1.2
Eukaryotic translation initiation factor 3, subunit 10 (theta) Eif3s10 1.0 0.75 1.09
DnaJ (Hsp40) homolog, subfamily B, member 1 Dnajb1 1.0 0.74 0.94
DnaJ (Hsp40) homolog, subfamily C, member 2 Dnajc2 1.0 0.60 0.81
DnaJ (Hsp40) homolog, subfamily A, member 3 Dnaja3 1.0 0.55 1.53
DnaJ (Hsp40) homolog, subfamily C, member 7 Dnajc7 1.0 0.77 0.99
Heat shock protein 110 Hsp110 1.0 0.61 1.13
Heat shock 70 kDa protein 14 Hsp14 1.0 0.57 0.9
  1. *Absent in control