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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice

Figure 1

Nitric oxide decreases cell adhesion molecule expression in the brain during Plasmodium berghei ANKA infection. Expression levels of ICAM-1, VCAM-1, P-selectin and E-selectin in the brain of uninfected and PbA-infected saline-treated and DPTA-NO-treated mice (day 6 of infection). Expression levels were normalized in relation to GAPDH expression. Saline-treated mice showed increased expression of ICAM-1, VCAM-1 and P-selectin, but not E-selectin. DPTA-NO treatment significantly decreased ICAM-1 and P-selectin, but not VCAM-1, expression. *: p < 0.05; **: p < 0.01; ***: p < 0.001.

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Journal of Neuroinflammation

ISSN: 1742-2094