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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis

Figure 1

Clinical Signs of Meningitis. All infected mice showed clinical signs of disease 18 h after injection, reflected in (A) an elevated clinical score and (B) a tenfold reduced explorative activity compared to uninfected controls. Two weeks after infection, animals that had received adjunctive dexamethasone treatment showed explorative activity similar to uninfected controls whereas explorative activity in animals that had received placebo or adjunctive NT-3 was still reduced. (#) P < 0.05 as compared to uninfected controls, (*) p < 0.05 as compared to infected animals receiving ceftriaxone and placebo.

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