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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Temporal and sequential changes of glial cells and cytokine expression during neuronal degeneration after transient global ischemia in rats

Figure 2

Reduction of NeuN+ cells after recirculation. A are microscopic images of a part of CA1 Py, indicated by the rectangle in Figure 1A, immunostained with an anti-NeuN antibody. On day3, NeuN+ cell reduction was observed. This reduction continued from day5 to day14. Graph B shows the reduction curve of NeuN+ cells in CA1 Py. In this graph, NeuN+ cell percentage is calculated by dividing the no. of NeuN+ cell in 4VO by the no. of NeuN+ cell in the normal rats in an area of the same size. Each data point shows the mean ± SEM of results from 5 rats. The amount of NeuN+ cells in CA1 on day3, 5, 7, 14 and 21 were 90 ± 5.1, 55 ± 2.1, 34 ± 3.5, 12 ± 2.3% and 17 ± 5%, respectively. The process of neuronal reduction after recirculation was divided into 4 phases: lag, exponential, deceleration and stationary phases.

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Journal of Neuroinflammation

ISSN: 1742-2094