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Table 1 Cytokines expressed significantly higher or lower than sham in each phase of neuronal reduction. P < 0.05 by t-test

From: Temporal and sequential changes of glial cells and cytokine expression during neuronal degeneration after transient global ischemia in rats

 

~lag phase

exponential phase

deceleration phase

stationary phase~

day after recirculation

day1

day2

day3

day5

day7

day10

day14

day21

 

IL1α, IL-6

IL-1α, IL-1β

IL-1α, IL-1β

IL-1α, IL-4

IL-1β

IL-1α, IL-1β

IL-1α, IL-4

IL-1α, IL-1β

higher

 

IL-4, IL-6

IL-6, IFN-γ

IFN-γ

 

IL-4, IL-6

IL-6,GM-CSF

IL-4, IL-6

      

GM-CSF,

IFN-γ, TNF-α

IFN-γ,TNF-α

      

TNF-α

  

lower

none

none

none

none

IL-2

none

none

IL-2