Effect of GSNO on reduction of infarction after TBI. Representative TTC-stained brain section (#3 out of the six consecutive sections from cranial to caudate region) corresponding to the largest infarction (A) and infarct area (B) from each group. Brain sections (2 mm thick) were stained with TTC at 48 h after CCI to show the area of infarctions. The infarctions were not observed in the sham group. The area under the rectangle on GSNO section was used for IHC and histology studies. Data are presented as means ± SD from three different experiments. *** p < 0.001 vs. TBI.