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Table 1 Physiologic parameters

From: S-Nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats

 

Sham

Injured (CCI)

 

Untreated

GSNO-treated

SIN-1-treated

Untreated (TBI)

GSNO-treated (GSNO)

SIN-1 treated (SIN-1)

 

Basal

3 h

Basal

3 h

Basal

3 h

Basal

3 h CCI

Basal

3 h CCI

Basal

3 h CCI

Rectal

Temp (°C)

37.3 ± .3

37.2 ± .2

37.3 ± .2

36.9 ± .2

37.2 ± .1

36.8 ± .4

37.3 ± .2

36.6 ± .4

37.3 ± .3

36.7 ± .2

37.3 ± .2

36.6 ± .3

MABP (mm Hg)

123 ± 12

121 ± 11

122 ± 10

120 ± 12

122 ± 12

119 ± 13

121 ± 12

97 ± 14

116 ± 10

95 ± 9

118 ± 7

91 ± 8

HR (beat/min)

396 ± 32

394 ± 31

394 ± 32

404 ± 35

395 ± 31

408 ± 29

395 ± 30

405 ± 25

382 ± 27

410 ± 40

385 ± 24

415 ± 30

  1. Measurements were performed before CCI (basal) and at 3 hours after CCI or 1 hour after drug administration (50 μg/kg body weight, oral). Data are presented as mean ± SD for n = 5 animals in each group. No significant differences were observed among untreated and treated groups of sham or injured animals. However, animals after CCI showed a trend of decreased MABP in the injured group. Basal, 30 min before CCI; Temp, temperature; MABP, mean arterial blood pressure; HR, heart rate.
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Journal of Neuroinflammation

ISSN: 1742-2094