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Table 1 Physiologic parameters

From: S-Nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats

  Sham Injured (CCI)
  Untreated GSNO-treated SIN-1-treated Untreated (TBI) GSNO-treated (GSNO) SIN-1 treated (SIN-1)
  Basal 3 h Basal 3 h Basal 3 h Basal 3 h CCI Basal 3 h CCI Basal 3 h CCI
Rectal
Temp (°C)
37.3 ± .3 37.2 ± .2 37.3 ± .2 36.9 ± .2 37.2 ± .1 36.8 ± .4 37.3 ± .2 36.6 ± .4 37.3 ± .3 36.7 ± .2 37.3 ± .2 36.6 ± .3
MABP (mm Hg) 123 ± 12 121 ± 11 122 ± 10 120 ± 12 122 ± 12 119 ± 13 121 ± 12 97 ± 14 116 ± 10 95 ± 9 118 ± 7 91 ± 8
HR (beat/min) 396 ± 32 394 ± 31 394 ± 32 404 ± 35 395 ± 31 408 ± 29 395 ± 30 405 ± 25 382 ± 27 410 ± 40 385 ± 24 415 ± 30
  1. Measurements were performed before CCI (basal) and at 3 hours after CCI or 1 hour after drug administration (50 μg/kg body weight, oral). Data are presented as mean ± SD for n = 5 animals in each group. No significant differences were observed among untreated and treated groups of sham or injured animals. However, animals after CCI showed a trend of decreased MABP in the injured group. Basal, 30 min before CCI; Temp, temperature; MABP, mean arterial blood pressure; HR, heart rate.