Figure 3

IFNβ inhibits progression of the cell cycle, though to a lesser extent than IFNγ. BrdU-incorporation of OPCs incubated with IFNβ (1 kU/ml, IFNβ) or IFNγ (100 ng/ml, IFNγ) for 24 (open bars) and 48 h (closed bars). OPCs were exposed to a 4 h-BrdU pulse immediately before fixation. ** Indicates p < 0.01 compared with control or in comparison between the two groups indicated.