Figure 4

Graphical representation of the IL-6 signaling pathway reveals significant gene expression changes following sarin-induced seizure. Genes in the IL-6 signaling pathway at the 6 h time point for sarin-induced seizing animals are represented as nodes of various shapes to represent the functional class of the gene product, and the biological relationship between two nodes is represented as a line. The intensity of the node color indicates the degree of up- (red) or down- (green) regulation. Nodes shown in gray represent genes from the dataset that did not meet the p-value cutoff, and nodes shown in white represent genes that are in IPA's Knowledge Base but not in the dataset.