Figure 3From: Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin Sarin-induced seizure up-regulates the expression of TNF-α in all five brain regions examined. Brain tissues were collected at 0.25, 1, 3, 6, and 24 h after seizure onset and processed for oligonucleotide microarray analysis. TNF-α expression was induced as early as 0.25 h following seizure onset, peaked at 3 h, and returned to near control levels by 24 h after seizure onset.Back to article page