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Table 2 Cycle threshold (Ct) values of mRNAs

From: TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

  

IL-1α

IL-1ß

IL-6

TGFß

CCL2

(MCP-1)

CCL3

(MIP-1α)

CCL4

(MIP-1ß)

CCL6

(C10)

GAPDH

9M

Neocortex

TLR4M

25.7 ± 0.35

28.8 ± 0.49

29.0 ± 0.44

22.3 ± 0.39

27.4 ± 0.74

28.1 ± 0.42

28.6 ± 0.37

23.5 ± 0.50

13.2 ± 0.22

 

TLR4W

24.5 ± 0.38

27.5 ± 0.30

28.6 ± 0.15

21.7 ± 0.30

27.2 ± 0.33

24.7 ± 0.36

26.2 ± 0.29

22.4 ± 0.23

13.4 ± 0.30

Hippocampus

TLR4M

25.5 ± 0.49

29.8 ± 0.57

29.2 ± 0.41

21.4 ± 0.20

28.03 ± 0.25

27.6 ± 0.34

29.2 ± 0.40

23.1 ± 0.22

12.8 ± 0.33

 

TLR4W

24.1 ± 0.29

27.4 ± 0.09

28.2 ± 0.13

20.6 ± 0.07

27.7 ± 0.29

24.7 ± 0.37

26.6 ± 0.30

20.7 ± 0.24

12.6 ± 0.35

5M

Neocortex

TLR4M

29.2 ± 0.50

29.5 ± 0.54

29.1 ± 0.45

23.2 ± 0.41

31.6 ± 0.93

27.4 ± 0.51

28.9 ± 0.42

24.24 ± 0.23

15.5 ± 0.45

 

TLR4W

27.5 ± 0.20

28.9 ± 0.24

27.1 ± 0.28

21.9 ± 0.10

29.5 ± 0.83

26.8 ± 0.13

27.7 ± 0.44

22.6 ± 0.29

14.6 ± 0.43

Hippocampus

TLR4M

26.2 ± 0.34

29.2 ± 0.33

28.2 ± 0.06

22.0 ± 0.40

28.3 ± 0.49

26.9 ± 0.62

29.0 ± 0.48

23.8 ± 0.34

14.1 ± 0.22

 

TLR4W

24.9 ± 0.24

28.4 ± 0.24

27.2 ± 0.15

21.3 ± 0.22

26.9 ± 0.32

25.7 ± 0.54

28.5 ± 0.40

23.2 ± 0.69

14.0 ± 0.06