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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Aspirin-triggered lipoxin A4attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells

Figure 5

Inhibition of LPS-induced phosphorylation of ERK and p38 MAPK in BV-2 microglial cells. BV-2 cells were stimulated with 100 ng/ml LPS in the absence or presence of 100 nM ATL that had been added 30 min before activation. Levels of ERK and phosphorylated ERK (A), p38 and phosphorylated p38 (B), and JNK and phosphorylated JNK (C) were analyzed using western blotting 30 min after stimulation with LPS. The figures show representative results of three independent experiments. Each bar represents the means ± SEM. **P < 0.01 compared with LPS in the absence of ATL;# P <0.05 compared with vehicle; ## P < 0.01 compared with vehicle.

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Journal of Neuroinflammation

ISSN: 1742-2094