NCR1 mRNA expression in white matter lesions. NCR1 mRNA was investigated in whole tissue RNA extract from MS white matter lesions (WML) and control white matter. We compared levels of NCR1 mRNA and conducted a Mann Whitney test. NCR1 mRNA levels from MS WML were significantly (p = 0.0133) increased (3.418 ± 1.368) compared to controls (0.651 ± 0.246). XPNPEP1 were used as normaliser. Similar increased levels were confirmed with the more commonly used normaliser GAPDH (data not shown).