NCR1 expression in MS grey matter and in the parkinsonian brain. In the MS grey matter NCR1+ astrocytes were observed mostly restricted to the pia surface (A) and throughout, irrespective of the presence of areas of demyelination or not. In some cases however some intra-laminar NCR1+ astrocytes (B) were seen but very few NCR1+ astrocytes were detected in neuronal cortical layers. NCR1+ astrocytes were detected in the PD substantia nigra (B) and also in the frontal cortex (pia surface) of the parkinsonian brain (C). Scale = 20 μm (A, C & D), Scale = 40 μm (B).