Figure 6

METH increases TNFR1 and IL-6R-α protein levels. Quantification of (A) TNFR1 and (B) IL-6R-α protein levels in N9 microglial cells at 1 h and 24 h post-METH exposure, respectively. Above the bars, representative western blot images of TNFR1 (55 kDa), IL-6R-α (63 kDa) and actin (42 kDa) are shown. The results are expressed as mean percentage of control ± SEM (n = 3 to 15). ^* P <0.05, Mann–Whitney post-test, significantly different from control. IL-6R-α: interleukin-6 receptor-alpha; kDa: kiloDaltons; LPS: lipopolysaccharide; METH: methamphetamine; SEM: standard error of the mean; TNFR1: tumor necrosis factor receptor 1.