Skip to main content
Figure 4 | Journal of Neuroinflammation

Figure 4

From: Expression of Scavenger receptor A on antigen presenting cells is important for CD4+ T-cells proliferation in EAE mouse model

Figure 4

Reduction in cytokine release following MOG 35–55 immunization in SRA −/− vs. WT mice. Spleen cells from MOG35–55-immunized WT mice and SRA−/− mice (n = 11) were cultured in a 96-well plate at a concentration of 1 × 106 cells/well in the presence of 100 μg/ml MOG35-55. Culture supernatants were collected after 48 h for analysis of (A) IFN-γ, (B) IL-17, (C) IL-2, (D) TNF-α (E) IL-6 and (F) IL-10 by ELISA. SRA−/− splenocytes showed a significant reduction in cytokine production when compared to WT splenocytes. Results are presented as means ± SEM.

Back to article page