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Table 3 Linear mixed model results

From: Multiplex array proteomics detects increased MMP-8 in CSF after spinal cord injury

ID

Response difference

Raw P- value

BH adjusted P- value

MMP-8

32856.83

0.0000

0.0000

Thymus Chemokine-1

−8426.12

0.0163

0.3094

MCP-1

4878.50

0.1624

0.9978

TIMP-1

2416.63

0.4882

0.9978

IL-13

−1482.87

0.6705

0.9978

Agrin

658.13

0.8502

0.9978

TNF-α

383.13

0.9124

0.9978

Fractalkine

214.00

0.9510

0.9978

PDGF-AA

196.13

0.9551

0.9978

GM-CSF

187.25

0.9571

0.9978

IL-4

175.63

0.9598

0.9978

IL-2

171.75

0.9607

0.9978

VEGF

160.25

0.9633

0.9978

ICAM-1

152.88

0.9650

0.9978

Fas ligand

−138.75

0.9682

0.9978

IL-1β

126.50

0.9710

0.9978

LIX

124.75

0.9714

0.9978

β-NGF

120.75

0.9724

0.9978

L-selectin

118.38

0.9729

0.9978

MIP-3α

109.38

0.9750

0.9978

IL-10

100.13

0.9771

0.9978

B7-2/CD86

99.50

0.9772

0.9978

IL-1 R6

97.63

0.9776

0.9978

Leptin

71.13

0.9837

0.9978

IL-6

58.38

0.9866

0.9978

IL-1α

50.63

0.9884

0.9978

RAGE

30.00

0.9931

0.9978

Activin A

19.50

0.9939

0.9978

CINC-2α

−26.37

0.9940

0.9978

Prolactin-R

24.13

0.9945

0.9978

CINC-3

20.88

0.9952

0.9978

CNTF

16.63

0.9962

0.9978

CINC-1

14.63

0.9967

0.9978

IFN-γ

9.63

0.9978

0.9978

  1. BH, Benjamini-Hochburg; MMP, matrix metalloproteinase; TIMP-1, tissue inhibitor of metalloproteinase-1.
  2. Full table of results from mixed model sorted by raw P-value. The differences in means between injured and non-injured animals are displayed in the second column. Proteins with changes significant at the 5% level (BH adjusted P-values) are italicized.