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Table 1 Selection of single nucleotide polymorphisms within IL-6 gene

From: Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain

Gene

Gene position

Total no. of SNPs (MAF ≥0.01)

No. of tagging SNP

Mean r2

Selected SNPs

Position

Function

Alleles

MAF HapMapCEU

Alleles captured

Prediction (STAMPA)

IL-6

chr7: 22,731,750-22,738,790

43

22

0.991

rs1800795

22733170

5' near gene

CG

0.467 (G)

8

97.08%

rs1800796

22732771

5' near gene

CG

0.043 (C)

3

rs2069833

22734189

intron

CT

0.475 (T)

8

rs2069840

22735097

intron

CG

0.317 (G)

1

  1. SNP, single nucleotide polymorphism; MAF, minor allele frequency; r2, linkage disequilibrium statistic [49]. MAF data relates CEU population from HapMap Phase II + III [50].